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Methadone Clinics in San Antonio, Texas

5 SAMHSA-certified opioid treatment programs operate inside San Antonio city limits. Each clinic below carries a current NPI on the CMS Medicare Provider OTP file. We list the operator-stated phone next to our verified intake line so you choose how to make contact.

San Antonio, Texas

5 verified clinics in San Antonio

Bexar County Board OF Trustees FOR

601 N FRIO ST, BLDG 2, San Antonio, TX 78207 · Directions
SAMHSA-certified OTP per CMS-OTP-2026-01-05. NPI 1730134586.

San Antonio at a glance

1,458,954
Residents
498.9 sq mi
Land area
34.6
Median age
$62,917
Median household income
17.5%
Uninsured (civilian)
13.2%
Families below poverty

Source: U.S. Census Bureau, ACS 5-year estimates (2023).

Overdose context for Bexar County

Bexar County reported a model-based drug poisoning death rate of 22.4 per 100,000 residents in 2021 (95% CI 21.7 to 23.2). That sits 21.2% below the national county mean of 28.5 per 100,000.

201915
202019.4
202122.4

Three-year change (15 to 22.4): +7.4 per 100,000.

County-level estimates are reported at the county level, not the city level. Source: NCHS Drug Poisoning Mortality by County (CDC dataset rpvx-m2md), 2019 to 2021 model-based estimates. NCHS urban/rural classification: Large Central Metro.

Closest methadone clinic to San Antonio

Nearest verified opioid treatment program in Texas: Vcphcs Vii, LLC in Windcrest, about 9.2 miles (14.8 km) from San Antonio by straight-line distance. Driving time will run longer.

Why this matters for treatment access

Bexar County reports a 2021 drug poisoning death rate of 22.4 per 100,000, modestly below the national county mean of 28.5. Roughly 17.5% of residents lack health insurance, which is high enough that you should ask each clinic about sliding-scale fees and Medicaid acceptance before you commit. That works out to roughly 255,317 uninsured residents in San Antonio alone.

What to ask before you call

Methadone is a daily-dose program. That changes the questions you should be asking. Run through these before you commit to a clinic:

If the in-city options do not fit

Closest alternative inside Texas: Vcphcs Vii, LLC in Windcrest, about 9.2 miles from San Antonio. Office-based buprenorphine is also available locally and does not require daily clinic visits.

Nearby cities with methadone clinics

Need office-based treatment instead of a daily-dosed OTP? Many providers in San Antonio prescribe buprenorphine in office settings. See Suboxone providers in San Antonio.

Want a non-opioid alternative? See Texas Vivitrol providers for monthly extended-release naltrexone.

State-level access scoring, regulatory context, and the full directory live on the Texas methadone hub.