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Methadone Clinics in Appleton, Wisconsin

1 SAMHSA-certified opioid treatment program operates inside Appleton city limits. Each clinic below carries a current NPI on the CMS Medicare Provider OTP file. We list the operator-stated phone next to our verified intake line so you choose how to make contact.

Appleton, Wisconsin

1 verified clinic in Appleton

Appleton at a glance

74,873
Residents
25.4 sq mi
Land area
36.9
Median age
$77,450
Median household income
4.9%
Uninsured (civilian)
5.5%
Families below poverty

Source: U.S. Census Bureau, ACS 5-year estimates (2023).

Overdose context for Outagamie County

Outagamie County reported a model-based drug poisoning death rate of 16.4 per 100,000 residents in 2021 (95% CI 14.6 to 18.4). That sits 42.5% below the national county mean of 28.5 per 100,000.

201911
202014.2
202116.4

Three-year change (11 to 16.4): +5.4 per 100,000.

County-level estimates are reported at the county level, not the city level. Source: NCHS Drug Poisoning Mortality by County (CDC dataset rpvx-m2md), 2019 to 2021 model-based estimates. NCHS urban/rural classification: Medium Metro.

Closest methadone clinic to Appleton

Nearest verified opioid treatment program in Wisconsin: AMS OF Wisconsin LLC in Oshkosh, about 20.7 miles (33.3 km) from Appleton by straight-line distance. Driving time will run longer.

Why this matters for treatment access

Outagamie County reports a 2021 drug poisoning death rate of 16.4 per 100,000, materially below the national county mean of 28.5. Uninsured rates here run low (4.9%), so commercial insurance acceptance matters. Ask each clinic which payers they bill. That works out to roughly 3,669 uninsured residents in Appleton alone.

What to ask before you call

Methadone is a daily-dose program. That changes the questions you should be asking. Run through these before you commit to a clinic:

If the in-city options do not fit

Closest alternative inside Wisconsin: AMS OF Wisconsin LLC in Oshkosh, about 20.7 miles from Appleton. Office-based buprenorphine is also available locally and does not require daily clinic visits.

Nearby cities with methadone clinics

Need office-based treatment instead of a daily-dosed OTP? Many providers in Appleton prescribe buprenorphine in office settings. See the Wisconsin Suboxone provider directory for the closest prescriber.

Want a non-opioid alternative? See Wisconsin Vivitrol providers for monthly extended-release naltrexone.

State-level access scoring, regulatory context, and the full directory live on the Wisconsin methadone hub.