Methadone Clinics in Knoxville, Tennessee
2 SAMHSA-certified opioid treatment programs operate inside Knoxville city limits. Each clinic below carries a current NPI on the CMS Medicare Provider OTP file. We list the operator-stated phone next to our verified intake line so you choose how to make contact.
2 verified clinics in Knoxville
DRD Management INC
Knoxville at a glance
193,721
Residents
98.7 sq mi
Land area
33.3
Median age
$50,994
Median household income
11.3%
Uninsured (civilian)
13%
Families below poverty
Source: U.S. Census Bureau, ACS 5-year estimates (2023).
Overdose context for Knox County
Knox County reported a model-based drug poisoning death rate of 70.6 per 100,000 residents in 2021 (95% CI 68.1 to 73.3). That sits 148.2% above the national county mean of 28.5 per 100,000.
201947.2
202061.2
202170.6
Three-year change (47.2 to 70.6): +23.4 per 100,000.
County-level estimates are reported at the county level, not the city level. Source: NCHS Drug Poisoning Mortality by County (CDC dataset rpvx-m2md), 2019 to 2021 model-based estimates. NCHS urban/rural classification: Medium Metro.
Closest methadone clinic to Knoxville
Nearest verified opioid treatment program in Tennessee: THE Patricia Hall Talbott Legacy CE in Maryville, about 16.8 miles (27.1 km) from Knoxville by straight-line distance. Driving time will run longer.
Why this matters for treatment access
Knox County ran a 2021 drug poisoning death rate of 70.6 per 100,000, well above the national county mean of 28.5. About 11.3% of residents are uninsured. Most clinics in the area accept Medicaid; confirm before scheduling intake. That works out to roughly 21,890 uninsured residents in Knoxville alone.
What to ask before you call
Methadone is a daily-dose program. That changes the questions you should be asking. Run through these before you commit to a clinic:
- What time does dosing start, and what time does it close? Daily methadone often means a 6am window five or six days a week.
- Which insurance plans do you bill? Medicaid coverage for OTPs varies by state plan and managed-care organization.
- How long does intake take from first call to first dose? In some states it is same-day. In others it can run a week.
- What is your take-home schedule? Federal rules let stable patients earn take-home doses over time. Clinic policy on how fast you earn them differs.
- Do you offer counseling on-site or do I coordinate it elsewhere?
If the in-city options do not fit
Closest alternative inside Tennessee: THE Patricia Hall Talbott Legacy CE in Maryville, about 16.8 miles from Knoxville. Office-based buprenorphine is also available locally and does not require daily clinic visits.
Nearby cities with methadone clinics
Maryville (1 · 27.8km) Newport (1 · 64.3km) Cleveland (1 · 120.9km) Chattanooga (1 · 162.7km) Murfreesboro (1 · 222.6km)
Need office-based treatment instead of a daily-dosed OTP? Many providers in Knoxville prescribe buprenorphine in office settings. See Suboxone providers in Knoxville.
Want a non-opioid alternative? See Tennessee Vivitrol providers for monthly extended-release naltrexone.
State-level access scoring, regulatory context, and the full directory live on the Tennessee methadone hub.