Methadone Clinics in Sioux Falls, South Dakota
1 SAMHSA-certified opioid treatment program operates inside Sioux Falls city limits. Each clinic below carries a current NPI on the CMS Medicare Provider OTP file. We list the operator-stated phone next to our verified intake line so you choose how to make contact.
1 verified clinic in Sioux Falls
Sioux Falls at a glance
197,642
Residents
83.6 sq mi
Land area
35.1
Median age
$74,714
Median household income
7.8%
Uninsured (civilian)
6.7%
Families below poverty
Source: U.S. Census Bureau, ACS 5-year estimates (2023).
Overdose context for Minnehaha County
Minnehaha County reported a model-based drug poisoning death rate of 18 per 100,000 residents in 2021 (95% CI 16.1 to 20.1). That sits 36.9% below the national county mean of 28.5 per 100,000.
201912
202015.6
202118
Three-year change (12 to 18): +5.9 per 100,000.
County-level estimates are reported at the county level, not the city level. Source: NCHS Drug Poisoning Mortality by County (CDC dataset rpvx-m2md), 2019 to 2021 model-based estimates. NCHS urban/rural classification: Small Metro.
Why this matters for treatment access
Minnehaha County reports a 2021 drug poisoning death rate of 18.0 per 100,000, materially below the national county mean of 28.5. About 7.8% of residents are uninsured. Most clinics in the area accept Medicaid; confirm before scheduling intake. That works out to roughly 15,416 uninsured residents in Sioux Falls alone.
What to ask before you call
Methadone is a daily-dose program. That changes the questions you should be asking. Run through these before you commit to a clinic:
- What time does dosing start, and what time does it close? Daily methadone often means a 6am window five or six days a week.
- Which insurance plans do you bill? Medicaid coverage for OTPs varies by state plan and managed-care organization.
- How long does intake take from first call to first dose? In some states it is same-day. In others it can run a week.
- What is your take-home schedule? Federal rules let stable patients earn take-home doses over time. Clinic policy on how fast you earn them differs.
- Do you offer counseling on-site or do I coordinate it elsewhere?
Need office-based treatment instead of a daily-dosed OTP? Many providers in Sioux Falls prescribe buprenorphine in office settings. See Suboxone providers in Sioux Falls.
Want a non-opioid alternative? See South Dakota Vivitrol providers for monthly extended-release naltrexone.
State-level access scoring, regulatory context, and the full directory live on the South Dakota methadone hub.