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Methadone Clinics in East Saint Louis, Illinois

1 SAMHSA-certified opioid treatment program operates inside East Saint Louis city limits. Each clinic below carries a current NPI on the CMS Medicare Provider OTP file. We list the operator-stated phone next to our verified intake line so you choose how to make contact.

1 verified clinic in East Saint Louis

Comprehensive Behavioral Health CEN

505 S 8TH ST, East Saint Louis, IL 62201 · Directions
SAMHSA-certified OTP per CMS-OTP-2026-01-05. NPI 1437328283.

East Saint Louis at a glance

Source: U.S. Census Bureau, ACS 5-year estimates (2023).

Why this matters for treatment access

What to ask before you call

Methadone is a daily-dose program. That changes the questions you should be asking. Run through these before you commit to a clinic:

Need office-based treatment instead of a daily-dosed OTP? Many providers in East Saint Louis prescribe buprenorphine in office settings. See the Illinois Suboxone provider directory for the closest prescriber.

Want a non-opioid alternative? See Illinois Vivitrol providers for monthly extended-release naltrexone.

State-level access scoring, regulatory context, and the full directory live on the Illinois methadone hub.