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Methadone Clinics in Los Angeles, California

5 SAMHSA-certified opioid treatment programs operate inside Los Angeles city limits. Each clinic below carries a current NPI on the CMS Medicare Provider OTP file. We list the operator-stated phone next to our verified intake line so you choose how to make contact.

Los Angeles, California

5 verified clinics in Los Angeles

Matrix Institute ON Addictions

5220 W WASHINGTON BLVD, STE 101, Los Angeles, CA 90016 · Directions
SAMHSA-certified OTP per CMS-OTP-2026-01-05. NPI 1235349267.

Narcotics Prevention Association IC

942 S ATLANTIC BLVD, Los Angeles, CA 90022 · Directions
SAMHSA-certified OTP per CMS-OTP-2026-01-05. NPI 1326181264.

Los Angeles at a glance

3,857,897
Residents
470.5 sq mi
Land area
36.9
Median age
$80,366
Median household income
10%
Uninsured (civilian)
11.9%
Families below poverty

Source: U.S. Census Bureau, ACS 5-year estimates (2023).

Overdose context for Los Angeles County

Los Angeles County reported a model-based drug poisoning death rate of 19 per 100,000 residents in 2021 (95% CI 18.7 to 19.3). That sits 33.3% below the national county mean of 28.5 per 100,000.

201912.7
202016.4
202119

Three-year change (12.7 to 19): +6.3 per 100,000.

County-level estimates are reported at the county level, not the city level. Source: NCHS Drug Poisoning Mortality by County (CDC dataset rpvx-m2md), 2019 to 2021 model-based estimates. NCHS urban/rural classification: Large Central Metro.

Closest methadone clinic to Los Angeles

Nearest verified opioid treatment program in California: American Health Services LLC in Venice, about 3.4 miles (5.4 km) from Los Angeles by straight-line distance. Driving time will run longer.

Why this matters for treatment access

Los Angeles County reports a 2021 drug poisoning death rate of 19.0 per 100,000, materially below the national county mean of 28.5. About 10.0% of residents are uninsured. Most clinics in the area accept Medicaid; confirm before scheduling intake. That works out to roughly 385,790 uninsured residents in Los Angeles alone.

What to ask before you call

Methadone is a daily-dose program. That changes the questions you should be asking. Run through these before you commit to a clinic:

If the in-city options do not fit

Closest alternative inside California: American Health Services LLC in Venice, about 3.4 miles from Los Angeles. Office-based buprenorphine is also available locally and does not require daily clinic visits.

Nearby cities with methadone clinics

Need office-based treatment instead of a daily-dosed OTP? Many providers in Los Angeles prescribe buprenorphine in office settings. See Suboxone providers in Los Angeles.

Want a non-opioid alternative? See California Vivitrol providers for monthly extended-release naltrexone.

State-level access scoring, regulatory context, and the full directory live on the California methadone hub.