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Methadone Clinics in Denver, Colorado

5 SAMHSA-certified opioid treatment programs operate inside Denver city limits. Each clinic below carries a current NPI on the CMS Medicare Provider OTP file. We list the operator-stated phone next to our verified intake line so you choose how to make contact.

Denver, Colorado

5 verified clinics in Denver

Comprehensive Behavioral Health CEN

2217 CHAMPA ST, Denver, CO 80205 · Directions
SAMHSA-certified OTP per CMS-OTP-2026-01-05. NPI 1669832382.

Regents OF THE University OF Colora

1620 GAYLORD ST, PARKSIDE CLINIC, Denver, CO 80206 · Directions
SAMHSA-certified OTP per CMS-OTP-2026-01-05. NPI 1235216532.

Denver at a glance

713,734
Residents
153.1 sq mi
Land area
35.2
Median age
$91,681
Median household income
8.8%
Uninsured (civilian)
7.7%
Families below poverty

Source: U.S. Census Bureau, ACS 5-year estimates (2023).

Overdose context for Denver County

Denver County reported a model-based drug poisoning death rate of 49.4 per 100,000 residents in 2021 (95% CI 47.6 to 51.2). That sits 73.5% above the national county mean of 28.5 per 100,000.

201933
202042.8
202149.4

Three-year change (33 to 49.4): +16.4 per 100,000.

County-level estimates are reported at the county level, not the city level. Source: NCHS Drug Poisoning Mortality by County (CDC dataset rpvx-m2md), 2019 to 2021 model-based estimates. NCHS urban/rural classification: Large Central Metro.

Closest methadone clinic to Denver

Nearest verified opioid treatment program in Colorado: Denver Recovery Group LLC in Aurora, about 4.3 miles (6.8 km) from Denver by straight-line distance. Driving time will run longer.

Why this matters for treatment access

Denver County ran a 2021 drug poisoning death rate of 49.4 per 100,000, well above the national county mean of 28.5. About 8.8% of residents are uninsured. Most clinics in the area accept Medicaid; confirm before scheduling intake. That works out to roughly 62,809 uninsured residents in Denver alone.

What to ask before you call

Methadone is a daily-dose program. That changes the questions you should be asking. Run through these before you commit to a clinic:

If the in-city options do not fit

Closest alternative inside Colorado: Denver Recovery Group LLC in Aurora, about 4.3 miles from Denver. Office-based buprenorphine is also available locally and does not require daily clinic visits.

Nearby cities with methadone clinics

Need office-based treatment instead of a daily-dosed OTP? Many providers in Denver prescribe buprenorphine in office settings. See Suboxone providers in Denver.

Want a non-opioid alternative? See Colorado Vivitrol providers for monthly extended-release naltrexone.

State-level access scoring, regulatory context, and the full directory live on the Colorado methadone hub.